Wertz X., Schoevaert D., Maitournam H., Chassignet P., Schwartz L.
he effect of hormones on bone growth is mediated through mechanical stresses
Mechanical constraints play a key role in regulating cell growth and
differentiation. Using data mechanical data available in the
literature, we are able to reconstruct a normal growth curve of a
child. It appears likely that the impact of hormones on pubertal
growth rate sprout followed by growth arrest, can be explained solely
by increased mechanical constraints. The uptake of hormones by the
muscles results in increased mechanical stresses on the chondrocyte
before and at puberty, resulting growth sprout followed by growth
cessation.
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